18/2/2016

obesityThe prevalences of both ever-asthma and recent asthma were higher in women (10.0% and 6.0%) than in men (5.7% and 2.7%, respectively). Obesity was prevalent in this rural town, with 38.2% of men and 33.7% of women having a BMI > 30 kg/m2. The mean of BMI was 29.2 kg/m2 for men and 28.4 kg/m2 for women. Seventy-four men (8.3%) and 120 women (10.3%) refused to have their WC measured, and their average BMIs were similar when compared to the overall averages (Table 1), suggesting that overweight or obesity is not likely an important reason for the missing data.

Table 2 shows that the prevalence of asthma was increased with increasing BMI and WC in women but not in men. For both ever-asthma and recent asthma, the prevalence was approximately twofold higher in women with a BMI of 30 kg/m2 compared with those with a BMI < 25 kg/m2, or in women with a WC of 100 cm vs those with a WC of < 100 cm.

Table 3 shows the prevalence of ever-asthma stratified by other potential risk factors including age, home environment variables, allergy history, education, income, smoking, and alcohol use. Respiratory allergy was strongly associated with asthma in both men and women. Home dampness was a determinant for asthma only in women. In women more so than men, the prevalence of asthma tended to be lower for regular alcohol drinkers than nondrinkers. Asthma is a deteriorating disorder but it may be efficiently overcome with remedies of My Canadian Pharmacy (get more information about My Canadian Pharmacy).

A multiple logistic regression model was used to assess the independent effect of BMI and WC on the prevalence of asthma after controlling for potential confounders in women and men. For ever asthma, the adjusted odds ratios (ORs) for women with a BMI of at least 30 kg/m2 and a BMI of 25.0 to 29.9 kg/m2 compared with a BMI of < 25 kg/m2 were 2.06 (95% CI, 1.42 to 4.05) and 1.62 (95% CI, 0.93 to 2.83), respectively (Table 4). The corresponding ORs for recent asthma tended to be higher. The risk of asthma in women with a WC a 100 cm was approximately twofold higher than those with a WC < 100 cm (Table 4). Higher levels of BMI and WC were not associated with increased risks of ever-asthma and recent asthma in men (Table 5).

Table 1—Comparison of BMI by WC in Men and Women, the Humboldt Study, 2003

WC, cm BMI, kg/m2
Men Women
No. Mean SD No. Mean SD
< 100 391 25.9 2.8 800 26.1 4.0
> 100 431 32.3 4.4 241 36.5 5.6
Unknown 74 28.7 4.4 120 28.0 5.4
Total 896 29.2 4.9 1161 28.4 6.1

Table 2—Prevalence of Asthma Associated With BMI and WC, the Humboldt Study, 2003

Variables Men Women
No. Cases % No. Cases %
Ever asthma BMI, kg/m2
< 25 156 10 6.4 389 26 6.7
25 to 29.9 397 21 5.3 381 34 8.9
> 30 343 20 5.8 391 56 14.3*
WC, cm
< 100 391 21 5.4 800 66 8.3
> 100 431 22 5.1 241 37 15.4
Unknown 74 8 10.8 120 13 10.8*
Total 896 51 5.6 1,161 116 10.0
Recent asthma BMI, kg/m2
< 25 156 6 3.3 389 10 2.6
25 to 29.9 397 10 2.1 381 26 6.8
> 30 343 8 1.9 391 34 8.7*
WC, cm
< 100 391 9 2.3 800 37 4.6
a 100 431 10 2.3 241 24 10.0
Unknown 74 5 6.8 120 9 7.5*
Total 896 24 2.7 1,161 70 6.0

Table 3—Prevalence of Ever-Asthma According to Various Risk Factors, the Humboldt Study, 2003

Variables Men Women
No. Cases I

%

I

No.

Cases %
Age, yr
18 to 39 215 14 6.5 294 38 12.9
40 to 59 353 24 6.2 446 39 8.7
a 60 328 15 4.6 421 39 9.3
Size of household
<3 581 26 5.0 693 76 11.0
a3 368 25 6.8 461 40 8.7
Unknown 10 0 7 0
Bedrooms, No.
<4 511 28 5.5 671 73 10.9
a4 374 23 6.1 472 42 8.9
Unknown 11 0 18 1
Pets
No 627 33 5.3 816 74 9.1
Yes 269 18 6.7 345 42 12.2
Respiratory allergy
No 656 16 2.4 757 32 4.2
Yes 240 35 14.6t 404 84 20.8t
Educational level
Low 523 34 6.5 581 49 8.4
High 357 17 4.8 563 65 11.5
Unknown 16 0 17 2
Income
Low 344 14 4.1 492 56 11.4
High 363 23 6.3 401 37 9.2
Unknown 189 14 7.4 268 23 8.6
Smoking status
Nonsmoker 411 27 6.6 681 67 9.8
Ex-smoker 362 18 5.0 348 34 9.8
Smoker 123 6 4.9 132 15 11.4
Alcohol use
No 263 12 4.6 554 65 11.7
Yes 625 38 6.1 593 51 8.6*
Unknown 8 1 14 0
Household dampness
No 794 44 5.5 995 87 8.7
Yes 102 7 6.9 166 29 17.5t

Table 4—Unadjusted and Adjusted ORs and 95% CIs for Asthma in Relation to BMI and WC in Women, the Humboldt Study, 2003

Variables Unadjusted Adjusted
I

OR

95% CI OR 95% CI
Ever-asthma
BMI, kg/m2 < 25.0 1.00 1.00
25.0 to 29.9 1.37 0.80-2.33 1.62 0.93-2.83
> 30.0 2.33 1.44-3.80 2.06 1.42-4.05
WC, cm
< 100 1.00 1.00
> 100 2.02 1.31-3.11 1.87 1.18-2.98
Unknown 1.35 0.72-2.53 1.30 0.67-2.53
Recent asthma
BMI, kg/m2 < 25.0 1.00 1.00
25.0-29.9 2.78 1.32-5.84 3.23 1.57-6.99
> 30.0 3.61 1.76-7.41 3.47 1.64-7.32
WC, cm
< 100 1.00 1.00
> 100 2.28 1.34-3.09 1.95 1.11-3.43
Unknown 1.67 0.79-3.56 1.56 0.71-3.41

Table 5—Unadjusted and Adjusted ORs and 95% CIs for Asthma in Relation to Body Mass Index and Waist Circumference in Men, the Humboldt Study, 2003

Variables Unadjusted Adjusted
I

OR

95% CI OR 95% CI
Ever-asthma
BMI, kg/m2 < 25.0 1.00 1.00
25.0 to 29.9 0.82 0.38-1.77 0.75 0.33-1.74
a 30.0 0.90 0.41-1.98 0.79 0.34-1.83
WC, cm
< 100 1.00 1.00
a 100 0.95 0.51-1.75 0.99 0.51-1.93
Unknown 2.14 0.90-5.02 3.28 1.28-8.41
Recent asthma
BMI, kg/m2 < 25.0 1.00 1.00
25.0 to 29.9 0.65 0.23-1.81 0.62 0.21-1.87
a 30.0 0.60 0.20-1.75 0.51 0.16-1.62
WC, cm
< 100 1.00 1.00
a 100 1.01 0.41-2.51 1.02 0.39-2.67
Unknown 3.08 1.00-9.45 5.11 1.51-17.30